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Company News 2026-02-06
FILLDERM Releases Controlled Collagen Self-Assembly Technology
On the occasion of Lichun (Start of Spring), a time when the starry sky shines its brightest, the “Smart Construction of Collagen, Orderly Regeneration” 2026 FIMAN “Controlled Collagen Self-Assembly Technology” Ecosystem Launch Conference was grandly held in Changchun. FIMAN Board General Manager Chen Xinwei, FIMAN Board Deputy General Manager Zhao Qing, alongside medical aesthetic experts, industry leaders, and authoritative media from across the country, embarked on a journey to decode the “Star Chain” of collagen technology. Together, they witnessed FIMAN’s “Controlled Collagen Self-Assembly Technology Platform” leading the anti-aging revolution and rewriting the new order of intelligent collagen construction.
▉ Safety: Returning to the Essence of Medical Aesthetics, Holding the Bottom Line
Aging can be viewed as a chronic disease requiring periodic management, where intervention during the prevention phase is paramount. As medical aesthetic products are often used by consumers long-term and repeatedly, their long-term safety is crucial for lasting peace of mind and trust. “FIMAN has always regarded quality, long-term efficacy, and safety as its bottom line. FIMAN persists in taking safety to the extreme. Driven by the consumer’s demand for precise anti-aging that is safe and effective, and by continuously refining quality, we have created today’s FILLDERM,” stated FIMAN Board General Manager Chen Xinwei in his address.
▌ Activity: The Core Premise for Collagen’s Anti-Aging Efficacy
International journals have confirmed that collagen derived from the heart is better able to improve artificial heart function and organ maturity compared to that from the kidney or spleen. This demonstrates that compatibility determines efficacy. Extracted from SIM-12 medical cattle, FILLDERM adheres to the principle of “taking from skin, using for skin,” possessing irreplaceable biological compatibility.
Dr. Ma Yanyun, Youth Researcher, PhD Supervisor at the Institute of Biomedical Engineering and Technology Innovation, Fudan University, and Executive Director of the Shanghai Skin Health Concept Validation Center, shared cutting-edge research results on bovine active collagen at the conference. Experimental results prove that bovine active collagen is safe for the body and local skin, causing no irritating reactions. On one hand, it can significantly improve skin barrier function, enhancing skin elasticity and firmness; on the other hand, it increases dermal density by boosting the tightness and content of collagen fibers. This further proves that collagen extracted from bovine skin “better understands the needs of human skin.”
▌ Traceability: The Key Guarantee for Maintaining High Collagen Activity
Just as the quality of ingredients determines the flavor of a Michelin chef’s cuisine, the efficacy of collagen depends on its activity, and this activity stems from rigorous control at the source.
FIMAN has established China’s first EU-standard medical collagen cattle farm. Every head of cattle must undergo BSE (Mad Cow Disease) testing at Customs, undergoing a total of 18 inspections and quarantines throughout the process. Furthermore, to control endotoxins and reduce cell necrosis, every piece of cattle hide is kept strictly below 4°C and transported within a race-against-the-clock 8-hour window to meet “organ transplant” standards. This system strictly controls the quantity of microorganisms to the 10^5 level, far below the decay threshold (10^6) required for organ transplants.
▌ Controlled Collagen Self-Assembly Technology: The “Customized” Key to Matching Multi-Layer & Multi-Region Collagen
Active collagen naturally undergoes “Self-Assembly” within the skin, but collagen structures vary across different skin layers. Consumer demands also differ by region; for instance, they desire light and delicate effects around the eyes, but firm and fullness in the apple cheeks. Therefore, allowing collagen to assemble naturally cannot achieve multi-level, customized tissue reconstruction.
Thus, through over 20 years of scientific research and 30,000 experimental iterations, FIMAN has exclusively developed the “Controlled Collagen Self-Assembly Technology Platform.” This allows FILLDERM to precisely replicate nature’s “uncanny workmanship,” possessing “precise evolutionary power” and making the Self-Assembly process “controllable.”
At the conference, FIMAN R&D Director Dr. Li Hongqiang provided an in-depth interpretation of the technical core behind FILLDERM: “Collagen without order is just a pile of loose sand, easily metabolized and degraded. Only orderly collagen can act as the ‘reinforced steel bars’ supporting skin elasticity. Through Controlled Collagen Self-Assembly Technology, we obtain smart collagen with higher biological activity, capable of meeting future anti-aging needs for all levels of the human body. The future of Controlled Collagen Self-Assembly Technology is the future of growth on demand.”
The conference revealed that FIMAN is conducting joint school-enterprise research with Fudan University on collagen. With core collagen technology as the support, both parties will continue to explore multiple scenarios including skin repair, tissue filling, mucosal repair, regenerative medicine, and even nutrition.
Relying on this brand-new Controlled Collagen Self-Assembly Technology Platform, FIMAN has launched the 4.0 Smart Construction Collagen Series, and the upgraded product [FILLDERM PRO] has come into being!
▌ FILLDERM Pro Dazzling Premiere: The Masterpiece of FIMAN Research
At the conference, guests gathered points of light to form a vast starry sea, illuminating the big screen and witnessing the shocking debut of FILLDERM PRO, equipped with FIMAN’s exclusive Controlled Collagen Self-Assembly Technology! The 4.0 Smart Construction Series achieves the “customization” of collagen fibers for the first time, making the Controlled Collagen Self-Assembly process “controllable.” It introduces three fiber structures—Cloud-Bundles, Micro-Bundles, and Macro-Bundles—which can establish different collagen scaffolds in the superficial, middle, and deep layers of the skin, matching the structures of different layers to achieve comprehensive anti-aging.
This new series not only sparks a “technological revolution” but also upgrades a unique anti-counterfeiting system. Mr. Chen Xinwei previewed that in the second half of 2026, FIMAN will launch two new products targeting superficial and deep skin, responding to consumer demands for safety and efficacy with quality, and providing more reliable protection for consumer rights with technology.
▌ Ecosystem Co-construction: Letting Consumers Trust Beauty, Walk into Beauty, and Obtain Beauty
The finale of the conference presented the roundtable forum “Standardization and Transparency, Trust Leads to Far: Building a New Healthy Medical Aesthetic Ecosystem.” FIMAN invited thought leaders who have long cultivated talent training and promoted professional industry standards, as well as important partners who have grown with Fillderm (Fiman)—including Professor Shi Bing, Chairman of the Professional Committee of Plastic and Aesthetics of the Chinese Non-Government Medical Institutions Association; Dr. Wang Xiahe, Vice President of the Chinese Association of Plastics and Aesthetics, Founder of Shenzhen Sunshine Group and Ziylan International Anti-Aging Medical Aesthetic Conference; Ms. Hu Ling, Head of Chaos Shanghai Branch, Ecological Partner of Chaos College, and Chairman of the Chaos Business School Alumni Association; Mr. Yang Ke, Founder & CEO of Meixinglian and Head of Future Medical Aesthetic Leaders Camp; and Mr. Huang Huan, Co-founder of Yanzi Aesthetics Commune. They engaged in deep dialogue around the tangible needs of consumers and the sustainable development of the industry, exploring how medical aesthetics can return to its essence and move towards a safer, more transparent, and high-quality future.
Witnessed by all guests, FIMAN joined hands with partners in the ecosystem to officially launch the Medical Aesthetic Quality Alliance. At the conclusion of the conference, FIMAN Board Deputy General Manager Zhao Qing reiterated FIMAN’s vision and responsibility: “As population aging intensifies, the public’s demand for a better life will certainly grow upwards. This requires us to jointly build this ecosystem well, letting more people trust beauty, walk into beauty, and obtain beauty. This is our shared vision. To this end, FIMAN is willing to invest more safety guarantees for that 0.01% risk, providing consumers with safe, scientific, and sustainable long-term healthy aesthetic solutions. While breaking through the sharpness of technological boundaries, we guard the temperature of the industry ecosystem, steadily taking every step based on medical evidence, and making this path go further.”
▉ Safety: Returning to the Essence of Medical Aesthetics, Holding the Bottom Line
Aging can be viewed as a chronic disease requiring periodic management, where intervention during the prevention phase is paramount. As medical aesthetic products are often used by consumers long-term and repeatedly, their long-term safety is crucial for lasting peace of mind and trust. “FIMAN has always regarded quality, long-term efficacy, and safety as its bottom line. FIMAN persists in taking safety to the extreme. Driven by the consumer’s demand for precise anti-aging that is safe and effective, and by continuously refining quality, we have created today’s FILLDERM,” stated FIMAN Board General Manager Chen Xinwei in his address.
▌ Activity: The Core Premise for Collagen’s Anti-Aging Efficacy
International journals have confirmed that collagen derived from the heart is better able to improve artificial heart function and organ maturity compared to that from the kidney or spleen. This demonstrates that compatibility determines efficacy. Extracted from SIM-12 medical cattle, FILLDERM adheres to the principle of “taking from skin, using for skin,” possessing irreplaceable biological compatibility.
Dr. Ma Yanyun, Youth Researcher, PhD Supervisor at the Institute of Biomedical Engineering and Technology Innovation, Fudan University, and Executive Director of the Shanghai Skin Health Concept Validation Center, shared cutting-edge research results on bovine active collagen at the conference. Experimental results prove that bovine active collagen is safe for the body and local skin, causing no irritating reactions. On one hand, it can significantly improve skin barrier function, enhancing skin elasticity and firmness; on the other hand, it increases dermal density by boosting the tightness and content of collagen fibers. This further proves that collagen extracted from bovine skin “better understands the needs of human skin.”
▌ Traceability: The Key Guarantee for Maintaining High Collagen Activity
Just as the quality of ingredients determines the flavor of a Michelin chef’s cuisine, the efficacy of collagen depends on its activity, and this activity stems from rigorous control at the source.
FIMAN has established China’s first EU-standard medical collagen cattle farm. Every head of cattle must undergo BSE (Mad Cow Disease) testing at Customs, undergoing a total of 18 inspections and quarantines throughout the process. Furthermore, to control endotoxins and reduce cell necrosis, every piece of cattle hide is kept strictly below 4°C and transported within a race-against-the-clock 8-hour window to meet “organ transplant” standards. This system strictly controls the quantity of microorganisms to the 10^5 level, far below the decay threshold (10^6) required for organ transplants.
▌ Controlled Collagen Self-Assembly Technology: The “Customized” Key to Matching Multi-Layer & Multi-Region Collagen
Active collagen naturally undergoes “Self-Assembly” within the skin, but collagen structures vary across different skin layers. Consumer demands also differ by region; for instance, they desire light and delicate effects around the eyes, but firm and fullness in the apple cheeks. Therefore, allowing collagen to assemble naturally cannot achieve multi-level, customized tissue reconstruction.
Thus, through over 20 years of scientific research and 30,000 experimental iterations, FIMAN has exclusively developed the “Controlled Collagen Self-Assembly Technology Platform.” This allows FILLDERM to precisely replicate nature’s “uncanny workmanship,” possessing “precise evolutionary power” and making the Self-Assembly process “controllable.”
At the conference, FIMAN R&D Director Dr. Li Hongqiang provided an in-depth interpretation of the technical core behind FILLDERM: “Collagen without order is just a pile of loose sand, easily metabolized and degraded. Only orderly collagen can act as the ‘reinforced steel bars’ supporting skin elasticity. Through Controlled Collagen Self-Assembly Technology, we obtain smart collagen with higher biological activity, capable of meeting future anti-aging needs for all levels of the human body. The future of Controlled Collagen Self-Assembly Technology is the future of growth on demand.”
The conference revealed that FIMAN is conducting joint school-enterprise research with Fudan University on collagen. With core collagen technology as the support, both parties will continue to explore multiple scenarios including skin repair, tissue filling, mucosal repair, regenerative medicine, and even nutrition.
Relying on this brand-new Controlled Collagen Self-Assembly Technology Platform, FIMAN has launched the 4.0 Smart Construction Collagen Series, and the upgraded product [FILLDERM PRO] has come into being!
▌ FILLDERM Pro Dazzling Premiere: The Masterpiece of FIMAN Research
At the conference, guests gathered points of light to form a vast starry sea, illuminating the big screen and witnessing the shocking debut of FILLDERM PRO, equipped with FIMAN’s exclusive Controlled Collagen Self-Assembly Technology! The 4.0 Smart Construction Series achieves the “customization” of collagen fibers for the first time, making the Controlled Collagen Self-Assembly process “controllable.” It introduces three fiber structures—Cloud-Bundles, Micro-Bundles, and Macro-Bundles—which can establish different collagen scaffolds in the superficial, middle, and deep layers of the skin, matching the structures of different layers to achieve comprehensive anti-aging.
This new series not only sparks a “technological revolution” but also upgrades a unique anti-counterfeiting system. Mr. Chen Xinwei previewed that in the second half of 2026, FIMAN will launch two new products targeting superficial and deep skin, responding to consumer demands for safety and efficacy with quality, and providing more reliable protection for consumer rights with technology.
▌ Ecosystem Co-construction: Letting Consumers Trust Beauty, Walk into Beauty, and Obtain Beauty
The finale of the conference presented the roundtable forum “Standardization and Transparency, Trust Leads to Far: Building a New Healthy Medical Aesthetic Ecosystem.” FIMAN invited thought leaders who have long cultivated talent training and promoted professional industry standards, as well as important partners who have grown with Fillderm (Fiman)—including Professor Shi Bing, Chairman of the Professional Committee of Plastic and Aesthetics of the Chinese Non-Government Medical Institutions Association; Dr. Wang Xiahe, Vice President of the Chinese Association of Plastics and Aesthetics, Founder of Shenzhen Sunshine Group and Ziylan International Anti-Aging Medical Aesthetic Conference; Ms. Hu Ling, Head of Chaos Shanghai Branch, Ecological Partner of Chaos College, and Chairman of the Chaos Business School Alumni Association; Mr. Yang Ke, Founder & CEO of Meixinglian and Head of Future Medical Aesthetic Leaders Camp; and Mr. Huang Huan, Co-founder of Yanzi Aesthetics Commune. They engaged in deep dialogue around the tangible needs of consumers and the sustainable development of the industry, exploring how medical aesthetics can return to its essence and move towards a safer, more transparent, and high-quality future.
Witnessed by all guests, FIMAN joined hands with partners in the ecosystem to officially launch the Medical Aesthetic Quality Alliance. At the conclusion of the conference, FIMAN Board Deputy General Manager Zhao Qing reiterated FIMAN’s vision and responsibility: “As population aging intensifies, the public’s demand for a better life will certainly grow upwards. This requires us to jointly build this ecosystem well, letting more people trust beauty, walk into beauty, and obtain beauty. This is our shared vision. To this end, FIMAN is willing to invest more safety guarantees for that 0.01% risk, providing consumers with safe, scientific, and sustainable long-term healthy aesthetic solutions. While breaking through the sharpness of technological boundaries, we guard the temperature of the industry ecosystem, steadily taking every step based on medical evidence, and making this path go further.”