FIMAN Attends C-Beauty | Rebuilding the ECM, Pioneering the Future of Intelligent Collagen

The next era of aesthetic medicine is no longer about filling the skin with materials—it’s about restoring order within the ECM.

From September 15–16, the 5th C-Beauty China Medical Aesthetics Industry Chain Forum 2026 was held in Guangzhou under the theme “Empowering Aesthetics through Scientific Innovation. ”
The forum focused on two key areas—injectable aesthetics and the convergence of cosmetics and medical devices—bringing together leading domestic and international companies, industry experts, and chief scientists from the medical aesthetics sector for in-depth discussions on the future of aesthetic innovation.

Ms. Zhao Qing Vice President of FIMAN, was invited to attend the event. She delivered a presentation titled From Disorder to Intelligent Construction: The Revolution of Controlled Self-Assembly of Active Collagen, and joined the roundtable discussion “Biomaterial Innovation: Reshaping the New Cycle of the Medical Aesthetics Industry”, where she thoroughly unpacked collagen’s development trends, innovative practices and technical logic.


Industry Overview: 
The Rise of Collagen, Capturing Premium Market Mindshare

In China’s injectable aesthetic market, hyaluronic acid and botulinum toxin have long been the dominant modalities in the mainstream segment. While collagen currently accounts for approximately 10% of the market, its growing adoption is positioning it as an increasingly important category within premium aesthetic medicine. While hyaluronic acid focuses on superficial filling and cosmetic modification, collagen delivers structural replenishment and tissue reconstruction.

Collagen serves as the carrier of mechanical order and the primary component of the extracellular matrix (ECM). The fundamental guarantee of collagen’s biological activity lies in its triple-helix structure. Leveraging its patented PET photo-controlled telopeptide removal technology, FIMAN achieves complete removal of immunogenic telopeptides while preserving the native triple-helix structure, giving rise to a more biologically active form of collagen—FILLDERM Collagen.

Technology Breakthrough: 
Intelligent Construction Revolution, Customizing the Order of Collagen Fibers

Collagen can spontaneously self-assemble into fibrils within the body, forming a structural network that provides tissue support. As Ms. Zhao Qing explains, “Under natural conditions, self-assembly is influenced by multiple variables and therefore remains difficult to control. It is much like planting a tree in nature—the way it grows and takes shape cannot be precisely determined. What FIMAN seeks to achieve is a shift from ‘spontaneous formation’ to ‘controlled formation. ’”

FIMAN’s proprietary Controlled Collagen Assembly (CCM) Technology Platform enables collagen molecules to assemble in a precisely designed manner, delivering tailored structural support across different tissue layers and advancing a truly layer-specific approach to aesthetic rejuvenation.
With more precise in situ integration, the collagen is more readily recognized and integrated by the body. Its enhanced resistance to enzymatic degradation may also contribute to greater durability over time.
True collagen quality lies in the order you can see—and the structure you can trust.


Research Validation: 
Full-Scenario Deployment to Remodel the ECM Microenvironment

A collaborative study conducted by FIMAN and Fudan University demonstrated that FIMAN Collagen may help restore a more youthful ECM structure and cellular microenvironment.
The research also revealed a notable finding: FIMAN Collagen demonstrated melanin-inhibiting activity comparable to that of 377, while engaging multiple pathways associated with skin-brightening effects.

FIMAN has developed three application pathways across injectable, topical, and oral administration, advancing comprehensive homeostatic remodeling of the dermal ECM microenvironment.

Injectable: As one of China’s early collagen-based injectable products to receive Class III medical device registration, FILLDERM is designed for precise dermal-layer augmentation.
Rather than functioning solely as a volume filler, FILLDERM is designed to support structural replenishment and sustained collagen-related regeneration. It provides immediate in situ support while promoting longer-term tissue rejuvenation—helping achieve natural-looking results without the excessive volumization typically associated with conventional filling approaches.

Topical & Oral: FIMAN has developed a transdermal recombinant human collagen platform and identified the innovative transdermal peptide ARK-TPP, designed to facilitate the efficient delivery of active ingredients through intercellular pathways with enhanced penetration and delivery efficiency.
BIOYONCE RESERVE VITALIZING ESSENCE is a representative product powered by this technology. It is designed to help soothe the sensations of pain, heat, and tightness following energy-based aesthetic treatments, while supporting the reduction of persistent redness.

Meanwhile, a growing body of research has demonstrated the potential benefits of oral collagen peptides in supporting skin health and addressing visible signs of skin ageing.
BIOYONCE COLLAGEN PEPTIDE SODIUM HYALURONATE DRINK, formulated around a four-collagen-peptide complex, helps support skin hydration and radiance while providing comprehensive nutritional support across the skin.
BIOYONCE COLLAGEN PEPTIDE CAVIARLIQUID DRINK combines collagen with traditional Chinese botanical ingredients, offering a multi-dimensional approach to soothing inflammation, reducing redness,supporting skin recovery, and strengthening the skin barrier.

“The ultimate value of collagen lies in ECM reconstruction. Injection, topical application, and oral administration are merely different modalities. What FIMAN truly aims to accomplish is restoring the microenvironment that supports cellular function, enabling the skin to regain its intrinsic regenerative capacity,” said Ms. Zhao Qing.  

The future of China’s collagen industry will be built on products backed by rigorous scientific evidence—and shaped by pioneers who truly understand collagen, master its potential, and continue to push the boundaries of its applications.  

Ms. Zhao Qing stated: “Every step FIMAN takes is grounded in rigorous science and guided by evidence-based practice. Aspirations for a better life and authentic beauty keep evolving. With a clear sense of purpose, FIMAN is committed to advancing innovation and delivering products supported by clinical evidence — meeting the evolving needs of aesthetic consumers and answering every expectation for beauty. ”